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My son also had developmental delays undiagnosed cause from the time he was a baby. He had always been low energy but not sleepy and we didn't think the Periactin was having any affect on energy nor did it seem to be making him tired. But once we finished treatment with this drug, within 48 hours, his doctors, therapists, family, and friends were noticing a dramatic difference in energy and engagement levels. From that time on, his developmental progress has accelerated, and his doctors assume the drug was very negatively affecting him, making him feel like he was in a fog at all times. He also very much struggled with potty training, which we began near the end of his time on Periactin. Even though he desperately wanted to potty train and was refusing to go back to diapers he was having 8-10 accidents a day for months and just didn't seem to have the ability to "hold it". Again, within 48 hours of stopping Periactin treatment, his potty training improved dramatically, with accidents suddenly decreasing to just once a day or so. So while Periactin did certainly increase my son's appetite, the negative side effects that we now recognized in hindsight absolutely were not worth it. Surely there would have been an equally effective drug or treatment without the harmful developmentally-stunting effect.
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